作者
Stephen Kadlecek, Kiarash Emami, Masaru Ishii, Rahim Rizi
发表日期
2010/7/1
期刊
Journal of Magnetic Resonance
卷号
205
期号
1
页码范围
9-13
出版商
Academic Press
简介
Intramolecular spin-order transfer is an useful technique for signal enhancement of insensitive and low-concentration molecular species. We present a closed-form, optimized pulse sequence which maximizes the efficiency of transfer between a singlet (para) nuclear pair and a vicinal heteronucleus. Neglecting the decay of coherences while the nuclei are in the transverse plane, the scheme is unity efficient for all combinations of internuclear scalar couplings. Efficiency loss due to T2-like decay is also minimized by keeping the sequence as short as possible. We expect this result to be useful for hyperpolarization experiments in which the spin-order originates in parahydrogen, as well as studies of singlet state decay aimed at longer-term storage of spin-order in hyperpolarized Magnetic Resonance Imaging.
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