作者
Diego Martinez, Jean Challacombe, Ingo Morgenstern, David Hibbett, Monika Schmoll, Christian P Kubicek, Patricia Ferreira, Francisco J Ruiz-Duenas, Angel T Martinez, Phil Kersten, Kenneth E Hammel, Amber Vanden Wymelenberg, Jill Gaskell, Erika Lindquist, Grzegorz Sabat, Sandra Splinter BonDurant, Luis F Larrondo, Paulo Canessa, Rafael Vicuna, Jagjit Yadav, Harshavardhan Doddapaneni, Venkataramanan Subramanian, Antonio G Pisabarro, José L Lavín, José A Oguiza, Emma Master, Bernard Henrissat, Pedro M Coutinho, Paul Harris, Jon Karl Magnuson, Scott E Baker, Kenneth Bruno, William Kenealy, Patrik J Hoegger, Ursula Kües, Preethi Ramaiya, Susan Lucas, Asaf Salamov, Harris Shapiro, Hank Tu, Christine L Chee, Monica Misra, Gary Xie, Sarah Teter, Debbie Yaver, Tim James, Martin Mokrejs, Martin Pospisek, Igor V Grigoriev, Thomas Brettin, Dan Rokhsar, Randy Berka, Dan Cullen
发表日期
2009/2/10
期刊
Proceedings of the National Academy of Sciences
卷号
106
期号
6
页码范围
1954-1959
出版商
National Academy of Sciences
简介
Brown-rot fungi such as Postia placenta are common inhabitants of forest ecosystems and are also largely responsible for the destructive decay of wooden structures. Rapid depolymerization of cellulose is a distinguishing feature of brown-rot, but the biochemical mechanisms and underlying genetics are poorly understood. Systematic examination of the P. placenta genome, transcriptome, and secretome revealed unique extracellular enzyme systems, including an unusual repertoire of extracellular glycoside hydrolases. Genes encoding exocellobiohydrolases and cellulose-binding domains, typical of cellulolytic microbes, are absent in this efficient cellulose-degrading fungus. When P. placenta was grown in medium containing cellulose as sole carbon source, transcripts corresponding to many hemicellulases and to a single putative β-1–4 endoglucanase were expressed at high levels relative to glucose-grown …
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D Martinez, J Challacombe, I Morgenstern, D Hibbett… - Proceedings of the National Academy of Sciences, 2009