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Objective:

To investigate whether exposure to high maternal concentrations of 25 (OH)-vitamin D in pregnancy poses any risk to the child.

Design:

Prospective study.

Setting:

Princess Anne Maternity Hospital, Southampton, UK.

Subjects:

A group of 596 pregnant women were recruited. A total of 466 (78%) children were examined at birth, 440 (74%) at age 9 months and 178 (30%) at age 9 years.

Methods:

Maternal 25 (OH)-vitamin D concentrations were measured in late pregnancy. Anthropometry of the child was recorded at birth, 9 months and 9 years. At 9 months, atopic eczema was assessed. At 9 years, children had an echocardiogram and a dual energy x-ray absorptiometry scan, blood pressure, arterial compliance and carotid intima-media thickness were measured and intelligence and psychological function assessed.

Results:

There were no associations between maternal 25 (OH)-vitamin D concentrations and …