作者
Yan Zheng, JoAnn E Manson, Changzheng Yuan, Matthew H Liang, Francine Grodstein, Meir J Stampfer, Walter C Willett, Frank B Hu
发表日期
2017/7/18
期刊
Jama
卷号
318
期号
3
页码范围
255-269
出版商
American Medical Association
简介
Importance
Data describing the effects of weight gain across adulthood on overall health are important for weight control.
Objective
To examine the association of weight gain from early to middle adulthood with health outcomes later in life.
Design, Setting, and Participants
Cohort analysis of US women from the Nurses’ Health Study (1976-June 30, 2012) and US men from the Health Professionals Follow-Up Study (1986-January 31, 2012) who recalled weight during early adulthood (at age of 18 years in women; 21 years in men), and reported current weight during middle adulthood (at age of 55 years).
Exposures
Weight change from early to middle adulthood (age of 18 or 21 years to age of 55 years).
Main Outcomes and Measures
Beginning at the age of 55 years, participants were followed up to the incident disease outcomes. Cardiovascular disease, cancer, and death were confirmed by medical records or the …
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Y Zheng, JAE Manson, C Yuan, MH Liang, F Grodstein… - Jama, 2017