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Organosolv pulping of bagasse was conducted following a central composite design using a two-level factorial plan involving three pulping variables (temperature: 190–210°C, time: 120–180min, organic solvent ratio: 40–60% dimethyl formamide). Responses of pulp and handsheets properties to the process variables were analyzed using statistical software (MINITAB 14). Using values of the independent variables the variation ranges considered provided the following optimum values of the dependent variables: 82.7% (yield), 92.9 (kappa number), 1.403% (ash), 370ml (freeness), 6290m (breaking length), 9.4 (folding endurance), 5.955mNm²g⁻¹ (Tear index) and 2.811kNg⁻¹ (Burst index) for pulps and handsheets. Results showed that acceptable physical and mechanical properties of pulps and papers similar the pulp used for bleaching could be achieved at 210°C for 150min and 50% DMF. These are the most …