查看文章

Purpose:

A novel property evaluation methodology was used to determine the elusive value for the human corneal coefficient of friction (CoF).

Methods:

Using a microtribometer on 28 fresh human donor corneas with intact epithelia, the CoF was determined in 4 test solutions (≥ 5 corneas/solution): tear-mimicking solution (TMS) in borate-buffered saline (TMS-PS), TMS in phosphate-buffered saline (TMS-PBS), TMS with HEPES-buffered saline (TMS-HEPES), and tear-like fluid in PBS (TLF-PBS).

Results:

Mean (SD) CoF values ranged from 0.006 to 0.015 and were 0.013 (0.010) in TMS-PS, 0.006 (0.003) in TMS-PBS, 0.014 (0.005) in TMS-HEPES, and 0.015 (0.009) in TLF-PBS. Statistically significant differences were shown for TMS-PBS versus TLF (P= 0.0424) and TMS-PBS versus TMS-HEPES (P= 0.0179), but not for TMS-PBS versus TMS-PS (P= 0.2389).

Conclusions:

Successful measurement of the fresh human …