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The earliest compounds forming Earth's first continental crust were magmatic rocks with tonalitic-trondhjemitic-granodioritic composition (TTGs). TTGs are widely seen as originating from melting of hydrated oceanic crust in subduction zones. Alternative models argue that they may have formed by melting within thickened mafic oceanic protocrust. To simulate formation of Eoarchean TTGs in different tectonic regimes, we combine for the first time the thermodynamic calculation of residual assemblages with subsequent modeling of trace element contents in TTGs. We compare water-absent partial melting of two hydrated starting compositions, a modern mid-oceanic-ridge basalt (MORB) and a typical Eoarchean arc tholeiite from the Isua Supracrustal Belt that represents the country rock of Earth's oldest TTGs in southern West Greenland. At 10 kbar, partial melting of MORB-like residues results in modeled TTG …