查看文章

Autologous skin cell suspensions (ASCS) are useful for treating burn wounds, including in adjunct with split thickness skin grafts (STSG) for full thickness injuries.

Careful wound care is crucial after ASCS application to prevent leakage out of the wound bed. Solution blow spinning (SBS) can be used to spray polymer fiber mats with varied flexibility, adhesion, and absorption. Wounds treated with ASCS and SBS dressings demonstrate equivalent re-epithelialization as those treated conventionally. SBS polymers are currently applied using commercial airbrushes with limited control of sterility, pressure, and deposition rate, and have only been evaluated when applied after ASCS. This work investigates a novel SBS prototype designed to address these limitations and simultaneously spray cells and dressings.

A SBS prototype was engineered combining …