作者
Hooman Kamel, Babak B Navi, Nandita Sriram, Dominic A Hovsepian, Richard B Devereux, Mitchell SV Elkind
发表日期
2014/4/3
期刊
New England Journal of Medicine
卷号
370
期号
14
页码范围
1307-1315
出版商
Massachusetts Medical Society
简介
Background
The postpartum state is associated with a substantially increased risk of thrombosis. It is uncertain to what extent this heightened risk persists beyond the conventionally defined 6-week postpartum period.
Methods
Using claims data on all discharges from nonfederal emergency departments and acute care hospitals in California, we identified women who were hospitalized for labor and delivery between January 1, 2005, and June 30, 2010. We used validated diagnosis codes to identify a composite primary outcome of ischemic stroke, acute myocardial infarction, or venous thromboembolism. We then used conditional logistic regression to assess each patient's likelihood of a first thrombotic event during sequential 6-week periods after delivery, as compared with the corresponding 6-week period 1 year later.
Results
Among the 1,687,930 women with a first recorded delivery, 1015 had a thrombotic …
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H Kamel, BB Navi, N Sriram, DA Hovsepian… - New England Journal of Medicine, 2014