作者
Shadi Yaghi, Yeseon P Moon, Consuelo Mora-McLaughlin, Joshua Z Willey, Ken Cheung, Marco R Di Tullio, Shunichi Homma, Hooman Kamel, Ralph L Sacco, Mitchell SV Elkind
发表日期
2015/6
期刊
Stroke
卷号
46
期号
6
页码范围
1488-1493
出版商
Lippincott Williams & Wilkins
简介
Background and Purpose
Although left atrial enlargement (LAE) increases incident stroke risk, the association with recurrent stroke is less clear. Our aim was to determine the association of LAE with recurrent stroke most likely related to embolism (cryptogenic and cardioembolic) and all ischemic stroke recurrences.
Methods
We followed 655 first ischemic stroke patients in the Northern Manhattan Stroke Study for ≤5 years. LA size from 2D echocardiography was categorized as normal LAE (52.7%), mild LAE (31.6%), and moderate–severe LAE (15.7%). We used Cox proportional hazard models to calculate the hazard ratios and 95% confidence intervals for the association of LA size and LAE with recurrent cryptogenic/cardioembolic and total recurrent ischemic stroke.
Results
LA size was available in 529 (81%) patients. Mean age at enrollment was 69±13 years; 45.8% were male, 54.0% Hispanic, and 18.5% had …
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S Yaghi, YP Moon, C Mora-McLaughlin, JZ Willey… - Stroke, 2015