作者
Lucy Gilbert, Olga Basso, John Sampalis, Igor Karp, Claudia Martins, Jing Feng, Sabrina Piedimonte, Louise Quintal, Agnihotram V Ramanakumar, Janet Takefman, Maria S Grigorie, Giovanni Artho, Srinivasan Krishnamurthy, DOvE Study Group
发表日期
2012/3/31
期刊
The lancet oncology
卷号
13
期号
3
页码范围
285-291
出版商
Elsevier
简介
Background
Around 90% of deaths from ovarian cancer are due to high-grade serous cancer (HGSC), which is frequently diagnosed at an advanced stage. Several cancer organisations made a joint recommendation that all women with specified symptoms of ovarian cancer should be tested with the aim of making an early diagnosis. In the Diagnosing Ovarian Cancer Early (DOvE) study we investigated whether open-access assessment would increase the rate of early-stage diagnosis.
Methods
Between May 1, 2008, and April 30, 2011, we enrolled women who were aged 50 years or older and who had symptoms of ovarian cancer. They were offered diagnostic testing with cancer antigen (CA-125) blood test and transvaginal ultrasonography (TVUS) at a central and a satellite open-access centre in Montreal, QC, Canada. We compared demographic characteristics of DOvE patients with those of women in the same …
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L Gilbert, O Basso, J Sampalis, I Karp, C Martins… - The lancet oncology, 2012
