作者
Thomas P Weber, Nikolaos I Stilianakis
发表日期
2008/11/1
来源
Journal of infection
卷号
57
期号
5
页码范围
361-373
出版商
WB Saunders
简介
OBJECTIVES
The relative importance of airborne, droplet and contact transmission of influenza A virus and the efficiency of control measures depends among other factors on the inactivation of viruses in different environmental media.
METHODS
We systematically review available information on the environmental inactivation of influenza A viruses and employ information on infectious dose and results from mathematical models to assess transmission modes.
RESULTS
Daily inactivation rate constants differ by several orders of magnitude: on inanimate surfaces and in aerosols daily inactivation rates are in the order of 1–102, on hands in the order of 103. Influenza virus can survive in aerosols for several hours, on hands for a few minutes. Nasal infectious dose of influenza A is several orders of magnitude larger than airborne infectious dose.
CONCLUSIONS
The airborne route is a potentially important …
引用总数
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TP Weber, NI Stilianakis - Journal of infection, 2008