作者
L Marije Hofstra, Nicolas Sauvageot, Jan Albert, Ivailo Alexiev, Federico Garcia, Daniel Struck, David AMC Van de Vijver, Birgitta Åsjö, Danail Beshkov, Suzie Coughlan, Diane Descamps, Algirdas Griskevicius, Osamah Hamouda, Andrzej Horban, Marjo Van Kasteren, Tatjana Kolupajeva, Leondios G Kostrikis, Kirsi Liitsola, Marek Linka, Orna Mor, Claus Nielsen, Dan Otelea, Dimitrios Paraskevis, Roger Paredes, Mario Poljak, Elisabeth Puchhammer-Stöckl, Anders Sönnerborg, Danica Staneková, Maja Stanojevic, Kristel Van Laethem, Maurizio Zazzi, Snjezana Zidovec Lepej, Charles AB Boucher, Jean-Claude Schmit, Annemarie MJ Wensing, SPREAD Program, E Puchhammer-Stockl, M Sarcletti, B Schmied, M Geit, G Balluch, A-M Vandamme, J Vercauteren, I Derdelinckx, A Sasse, M Bogaert, H Ceunen, A De Roo, S De Wit, F Echahidi, K Fransen, J-C Goffard, P Goubau, E Goudeseune, J-C Yombi, P Lacor, C Liesnard, M Moutschen, D Pierard, R Rens, Y Schrooten, D Vaira, LPR Vandekerckhove, A Van den Heuvel, B Van Der Gucht, M Van Ranst, E Van Wijngaerden, B Vandercam, M Vekemans, C Verhofstede, N Clumeck, K Van Laethem, D Beshkov, I Alexiev, S Zidovec Lepej, J Begovac, L Kostrikis, I Demetriades, I Kousiappa, V Demetriou, J Hezka, M Linka, M Maly, L Machala, C Nielsen, LB Jørgensen, J Gerstoft, L Mathiesen, C Pedersen, H Nielsen, A Laursen, B Kvinesdal, K Liitsola, M Ristola, J Suni, J Sutinen, D Descamps, L Assoumou, G Castor, M Grude, P Flandre, A Storto, O Hamouda, C Kücherer, T Berg, P Braun, G Poggensee, M Däumer, J Eberle, H Heiken, R Kaiser, H Knechten, K Korn, H Müller, S Neifer, B Schmidt, H Walter, B Gunsenheimer-Bartmeyer, T Harrer, D Paraskevis, A Hatzakis, A Zavitsanou, A Vassilakis, M Lazanas, M Chini, A Lioni, V Sakka, S Kourkounti, V Paparizos, A Antoniadou, A Papadopoulos, G Poulakou, I Katsarolis, K Protopapas, G Chryssos, S Drimis, P Gargalianos, G Xylomenos, G Lourida, M Psichogiou, GL Daikos, NV Sipsas, A Kontos, MN Gamaletsou, G Koratzanis, H Sambatakou, H Mariolis, A Skoutelis, V Papastamopoulos, O Georgiou
发表日期
2016/3/1
期刊
Clinical infectious diseases
卷号
62
期号
5
页码范围
655-663
出版商
Oxford University Press
简介
Background. Numerous studies have shown that baseline drug resistance patterns may influence the outcome of antiretroviral therapy. Therefore, guidelines recommend drug resistance testing to guide the choice of initial regimen. In addition to optimizing individual patient management, these baseline resistance data enable transmitted drug resistance (TDR) to be surveyed for public health purposes. The SPREAD program systematically collects data to gain insight into TDR occurring in Europe since 2001.
Methods. Demographic, clinical, and virological data from 4140 antiretroviral-naive human immunodeficiency virus (HIV)–infected individuals from 26 countries who were newly diagnosed between 2008 and 2010 were analyzed. Evidence of TDR was defined using the WHO list for surveillance of drug resistance mutations. Prevalence of TDR was assessed …
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