作者
Giuseppe GL Biondi-Zoccai, Marzia Lotrionte, Antonio Abbate, Luca Testa, Enrico Remigi, Francesco Burzotta, Marco Valgimigli, Enrico Romagnoli, Filippo Crea, Pierfrancesco Agostoni
发表日期
2006/1/26
来源
Bmj
卷号
332
期号
7535
页码范围
202-209
出版商
British Medical Journal Publishing Group
简介
Objective To appraise multiple systematic reviews on the same clinical topic, focusing on predictors and correlates of quality of reporting of meta-analysis (QUOROM) scores.
Design Case study.
Setting Reviews providing at least individual quantitative estimates on role of acetylcysteine in the prevention of contrast associated nephropathy.
Data sources PubMed, the database of abstracts of reviews of effects, and the Cochrane database of systematic reviews (updated March 2005).
Main outcome measures Funding, compliance with the QUOROM checklist, scores on the Oxman and Guyatt quality index, and authors' recommendations.
Results 10 systematic reviews, published August 2003 to March 2005, were included. Nine pooled events despite heterogeneity and five recommended routine use of acetylcysteine, whereas the remaining studies called for further research. Compliance with the 18 items on the …
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GGL Biondi-Zoccai, M Lotrionte, A Abbate, L Testa… - Bmj, 2006