作者
Francesco Prati, Enrico Romagnoli, Laura Gatto, Alessio La Manna, Francesco Burzotta, Yukio Ozaki, Valeria Marco, Alberto Boi, Massimo Fineschi, Franco Fabbiocchi, Nevio Taglieri, Giampaolo Niccoli, Carlo Trani, Francesco Versaci, Giuseppe Calligaris, Gianni Ruscica, Alessandro Di Giorgio, Rocco Vergallo, Mario Albertucci, Giuseppe Biondi-Zoccai, Corrado Tamburino, Filippo Crea, Fernando Alfonso, Eloisa Arbustini
发表日期
2020/1/14
期刊
European Heart Journal
卷号
41
期号
3
页码范围
383-391
出版商
Oxford University Press
简介
Aims
The CLIMA study, on the relationship between coronary plaque morphology of the left anterior descending artery and twelve months clinical outcome, was designed to explore the predictive value of multiple high-risk plaque features in the same coronary lesion [minimum lumen area (MLA), fibrous cap thickness (FCT), lipid arc circumferential extension, and presence of optical coherence tomography (OCT)-defined macrophages] as detected by OCT. Composite of cardiac death and target segment myocardial infarction was the primary clinical endpoint.
Methods and results
From January 2013 to December 2016, 1003 patients undergoing OCT evaluation of the untreated proximal left anterior descending coronary artery in the context of clinically indicated coronary angiogram were prospectively enrolled at 11 independent centres (clinicaltrial.gov identifier NCT02883088 …
学术搜索中的文章
F Prati, E Romagnoli, L Gatto, A La Manna, F Burzotta… - European Heart Journal, 2020