作者
Francesco Burzotta, Antonio Maria Leone, Cristina Aurigemma, Aniello Zambrano, Giuseppe Zimbardo, Manfredi Arioti, Rocco Vergallo, Giovanni Luigi De Maria, Emma Cerracchio, Enrico Romagnoli, Carlo Trani, Filippo Crea
发表日期
2020/1/13
期刊
Cardiovascular Interventions
卷号
13
期号
1
页码范围
49-58
出版商
American College of Cardiology Foundation
简介
Objectives
The aim of this study was to compare optical coherence tomographic (OCT) guidance and fractional flow reserve (FFR) guidance in patients with angiographically intermediate coronary lesions (AICLs) in a single-center, prospective, 1:1 randomized trial.
Background
FFR and OCT imaging may help both in the assessment of AICLs and in percutaneous coronary intervention optimization.
Methods
Patients with AICLs were randomized to FFR or OCT imaging. In the FFR arm, PCI was performed if FFR was ≤0.80. In the OCT imaging arm, PCI was performed if area stenosis was ≥75% or 50% to 75% with minimal luminal area <2.5 mm2 or plaque rupture. Angina (evaluated using the Seattle Angina Questionnaire), major adverse cardiac events, and cost were assessed at the end of follow-up. The pre-defined primary endpoint was the composite of major adverse cardiac events or significant angina …
学术搜索中的文章
F Burzotta, AM Leone, C Aurigemma, A Zambrano… - Cardiovascular Interventions, 2020