查看文章

Background:

This study compares the microdose flare-up protocol to the ultrashort gonadotropinreleasing hormone (GnRH) agonist flare combined with the fixed multidose GnRH antagonist protocol in poor responders undergoing ovarian stimulation.

Materials and Methods:

In this randomized clinical trial, 120 women who were candidates for assisted reproductive techniques (ART) and had histories of one or more failed in vitro fertilization (IVF) cycles with three or fewer retrieved oocytes were prospectively randomized into two groups. Group I (60 patients) received the microdose flare-up regimen and group II (60 patients) received the ultrashort GnRH agonist combined with fixed GnRH antagonist.

Results:

There were no significant differences between the groups in the number of used gonadotropin ampoules (p= 0.591), duration of stimulation (p= 0.610), number of retrieved oocytes (p= 0.802), fertilization rate (p= 0 …