作者
Elvis Hysa, Milena Bond, Lisa Ehlers, Dario Camellino, Louise Falzon, Christian Dejaco, Frank Buttgereit, Daniel Aletaha, Andreas Kerschbaumer
发表日期
2024/2/1
来源
Rheumatology
卷号
63
期号
2
页码范围
285-297
出版商
Oxford University Press
简介
Objectives
To inform an international task force about current evidence on Treat to Target (T2T) strategies in PMR and GCA.
Methods
A systematic literature research (SLR) was conducted in Medline, EMBASE, Cochrane Library, clinicaltrials.gov from their inception date to May 2022, and in the EULAR/ACR abstract database (2019–2021). Randomised clinical trials (RCTs) and non-randomised interventional studies published in English and answering at least one of the eleven PICO questions on T2T strategies, treatment targets and outcomes, framed by the taskforce, were identified. Study selection process, data extraction and risk of bias assessment were conducted independently by two investigators.
Results
Of 7809 screened abstracts, 397 were selected for detailed review and 76 manuscripts were finally included (31 RCTs, eight subgroup …
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E Hysa, M Bond, L Ehlers, D Camellino, L Falzon… - Rheumatology, 2024