作者
Annamaria Colao, A Di Sarno, Paolo Cappabianca, Francesco Briganti, Rosario Pivonello, C Di Somma, Antongiulio Faggiano, Bernadette Biondi, Gaetano Lombardi
发表日期
2003/3
期刊
European Journal of Endocrinology
卷号
148
期号
3
页码范围
325-331
出版商
Oxford University Press
简介
Background
Gender differences in tumor size are supposed to exist in hyperprolactinemia since microadenomas are more commonly found in women and macroadenomas in men. Whether this reflects only a delay in diagnosis in men or a true gender difference in tumor pathogenesis is still unclear.
Objective
To prospectively analyze gender differences in the presentation and response to cabergoline treatment in 219 consecutive newly diagnosed patients with hyperprolactinemia.
Design
An open prospective design.
Subjects
Of the 219 patients of which 145 were women; 107 patients had macroprolactinoma, 97 had microprolactinoma, and 15 had non-tumoral hyperprolactinemia.
Methods
Presenting clinical symptoms, prolactin levels and tumor size at magnetic resonance imaging were measured before and 3 …
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A Colao, AD Sarno, P Cappabianca, F Briganti… - European Journal of Endocrinology, 2003