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Parenchyma-sparing surgery includes enucleation. Enucleation is not used very often, partly because of its technical complexity, and is usually reserved for anatomically favorable cases (> 3 mm from the duct of Wirsung) with benign etiology. We present a case demonstrating that it is always worth exploring the possibility of performing a more conservative surgery even in difficult anatomic locations [1, 3]. A 58-year-old woman was incidentally diagnosed with a 22× 18-mm neuroendocrine tumor in the posterior aspect of the pancreatic neck. It was< 2 mm from the main pancreatic duct, all along the lesion’s surface. Given this location and the long and intimate relationship between the lesion and the duct, confirmed by intraoperative ultrasound, enucleation was not considered a possibility: central pancreatectomy was proposed. However, careful intraoperative exploration allowed the identification of a cleavage plane …