作者
Carlos M Luna, Patricia Vujacich, Michael S Niederman, Carlos Vay, Carlos Gherardi, Josué Matera, Enrique C Jolly
发表日期
1997/3/1
期刊
Chest
卷号
111
期号
3
页码范围
676-685
出版商
Elsevier
简介
Study objective
To define the impact of BAL data on the selection of antibiotics and the outcomes of patients with ventilator-associated pneumonia (VAP).
Design
Prospective observation and bronchoscopy with BAL, performed within 24 h of establishing a clinical diagnosis of a new episode of hospital-acquired VAP or progression of a prior episode of nosocomial pneumonia (NP).
Setting
A 15-bed medical and surgical ICU.
Patients
One hundred thirty-two patients hospitalized for more than 72 h, who were mechanically ventilated and had a new or progressive lung infiltrate plus at least two of the following three clinical criteria for VAP: abnormal temperature (>38°C or <35°C), abnormal leukocyte count (>10,000/mm3 or <3,000/mm3), purulent bronchial secretions.
Interventions
Bronchoscopy with BAL within 24 h of establishing a clinical diagnosis of VAP or progression of an infiltrate due to prior VAP or NP. All patients …
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CM Luna, P Vujacich, MS Niederman, C Vay… - Chest, 1997