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To estimate the prevalence of self‐reported misuse of the antipsychotic quetiapine fumarate (quetiapine) among a sample of urban Australian people who inject drugs (PWID), and correlates of reported misuse in health and social domains.

Data were obtained from a national cross‐sectional convenience sample survey of 868 urban PWID.

Self‐reported life‐time and recent (past 6‐month) use, and mode of use, of prescribed and non‐prescribed quetiapine. ‘Misuse’ calculated on non‐oral use of the prescribed drug or non‐prescribed use. Self‐reported potential correlates of quetiapine misuse including socio‐demographic, drug use and health and social characteristics.

Thirty‐one per cent of the sample [95% confidence interval (CI) = 28–34%] reported ever misusing quetiapine, 15% (95% CI = 13–17%) in the preceding 6 months. Multivariate …