作者
Syed Shahzad Hasan, Toby Capstick, Raees Ahmed, Chia Siang Kow, Faizan Mazhar, Hamid A Merchant, Syed Tabish Razi Zaidi
发表日期
2020/11/1
来源
Expert review of respiratory medicine
卷号
14
期号
11
页码范围
1149-1163
出版商
Taylor & Francis
简介
Objectives
The acute respiratory distress syndrome (ARDS) secondary to viral pneumonitis is one of the main causes of high mortality in patients with COVID-19 (novel coronavirus disease 2019). We systematically reviewed mortality in COVID-19 patients with ARDS and the potential role of systemic corticosteroids in COVID-19 patients.
Methods
Electronic databases and country-specific healthcare databases were searched to identify relevant studies/reports. The quality assessment of individual studies was conducted using the Newcastle–Ottawa Scale. Country-specific proportion of individuals with COVID-19 who developed ARDS and reported death were combined in a random-effect meta-analysis to give a pooled mortality estimate of ARDS.
Results
The overall pooled mortality estimate among 10,815 ARDS cases in COVID-19 patients was 39% (95% CI: 23–56%). The pooled mortality estimate for China was 69 …
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SS Hasan, T Capstick, R Ahmed, CS Kow, F Mazhar… - Expert review of respiratory medicine, 2020