作者
Manuel Ribeiro da Silva, Daniela Linhares, Daniel Marques Vasconcelos, Cecilia Juliana Alves, Nuno Neves, Gilberto Costa, Meriem Lamghari
发表日期
2017/12
来源
BMC musculoskeletal disorders
卷号
18
页码范围
1-11
出版商
BioMed Central
简介
Background
Neuroimmune axis is central in the physiopathology of hip osteoarthritis (OA), but its specific pathways are still unclear. This systematic review aims to assess the nervous and immune system profile of patients with hip osteoarthritis (OA) when compared to healthy controls.
Methods
A systematic review followed PRISMA guidelines was conducted. A two-step selection process was completed, and from 609 references 17 were included. The inclusion criteria were: original articles on adult patients with hip OA, with assessment of neuroimmune expression. Articles with other interventions prior to analysis and those without a control group were excluded.
Results
Thirty-nine relevant neuroimmune markers were identified, with assessments in bone, cartilage, synovial membrane, synovial fluid, whole blood, serum …
学术搜索中的文章
MR da Silva, D Linhares, DM Vasconcelos, CJ Alves… - BMC musculoskeletal disorders, 2017