作者
Peter G Pappas, Barbara D Alexander, David R Andes, Susan Hadley, Carol A Kauffman, Alison Freifeld, Elias J Anaissie, Lisa M Brumble, Loreen Herwaldt, James Ito, Dimitrios P Kontoyiannis, G Marshall Lyon, Kieren A Marr, Vicki A Morrison, Benjamin J Park, Thomas F Patterson, Trish M Perl, Robert A Oster, Mindy G Schuster, Randall Walker, Thomas J Walsh, Kathleen A Wannemuehler, Tom M Chiller
发表日期
2010/4/15
期刊
Clinical Infectious Diseases
卷号
50
期号
8
页码范围
1101-1111
出版商
The University of Chicago Press
简介
Background. Invasive fungal infections (IFIs) are a major cause of morbidity and mortality among organ transplant recipients. Multicenter prospective surveillance data to determine disease burden and secular trends are lacking.
Methods. The Transplant-Associated Infection Surveillance Network (TRANSNET) is a consortium of 23 US transplant centers, including 15 that contributed to the organ transplant recipient dataset. We prospectively identified IFIs among organ transplant recipients from March, 2001 through March, 2006 at these sites. To explore trends, we calculated the 12-month cumulative incidence among 9 sequential cohorts.
Results. During the surveillance period, 1208 IFIs were identified among 1063 organ transplant recipients. The most common IFIs were invasive candidiasis (53%), invasive aspergillosis (19%), cryptococcosis …
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PG Pappas, BD Alexander, DR Andes, S Hadley… - Clinical Infectious Diseases, 2010
