作者
Marta Cortón, José I Botella-Carretero, Alberto Benguria, Gemma Villuendas, Angel Zaballos, José L San Millán, Héctor F Escobar-Morreale, Belén Peral
发表日期
2007/1/1
期刊
The Journal of Clinical Endocrinology & Metabolism
卷号
92
期号
1
页码范围
328-337
出版商
Oxford University Press
简介
Context: The polycystic ovary syndrome (PCOS) is frequently associated with visceral obesity, suggesting that omental adipose tissue might play an important role in the pathogenesis of the syndrome.
Objective: The objective was to study the expression profiles of omental fat biopsy samples obtained from morbidly obese women with or without PCOS at the time of bariatric surgery.
Design: This was a case-control study.
Settings: We conducted the study in an academic hospital.
Patients: Eight PCOS patients and seven nonhyperandrogenic women submitted to bariatric surgery because of morbid obesity.
Interventions: Biopsy samples of omental fat were obtained during bariatric surgery.
Main Outcome Measure: The main outcome measure was high-density oligonucleotide arrays.
Results: After statistical analysis, we identified …
引用总数
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M Cortón, JI Botella-Carretero, A Benguria… - The Journal of Clinical Endocrinology & Metabolism, 2007