作者
Kaitlin M March, Nancy N Chen, Crystal D Karakochuk, Antonia W Shand, Sheila M Innis, Peter Von Dadelszen, Susan I Barr, Michael R Lyon, Susan J Whiting, Hope A Weiler, Tim J Green
发表日期
2015/8/1
期刊
The American journal of clinical nutrition
卷号
102
期号
2
页码范围
402-410
出版商
Elsevier
简介
Background: Vitamin D supplementation is recommended for breastfed infants. Maternal supplementation beginning in gestation is a potential alternative, but its efficacy in maintaining infant 25-hydroxyvitamin D [25(OH)D] concentration after birth is unknown.
Objectives: We determined the effect of 3 doses of maternal vitamin D supplementation beginning in gestation and continued in lactation on infant serum 25(OH)D and compared the prevalence of infant serum 25(OH)D cutoffs (>30, >40, >50, and >75 nmol/L) by dose at 8 wk of age.
Design: Pregnant women (n = 226) were randomly allocated to receive 10, 25, or 50 μg vitamin D3/d from 13 to 24 wk of gestation until 8 wk postpartum, with no infant supplementation. Mother and infant blood was collected at 8 wk postpartum.
Results: At 8 wk postpartum, mean [nmol/L (95% CI)] infant 25(OH)D at 8 wk was higher in the 50-μg/d [75 (67, 83)] than in the 25-μg/d [52 …
学术搜索中的文章
KM March, NN Chen, CD Karakochuk, AW Shand… - The American journal of clinical nutrition, 2015