作者
Xiangdong Liu, Pietro Invernizzi, Yue Lu, Roman Kosoy, Yan Lu, Ilaria Bianchi, Mauro Podda, Chun Xu, Gang Xie, Fabio Macciardi, Carlo Selmi, Sara Lupoli, Russell Shigeta, Michael Ransom, Ana Lleo, Annette T Lee, Andrew L Mason, Robert P Myers, Kevork M Peltekian, Cameron N Ghent, Francesca Bernuzzi, Massimo Zuin, Floriano Rosina, Elisabetta Borghesio, Annarosa Floreani, Roberta Lazzari, Grazia Niro, Angelo Andriulli, Luigi Muratori, Paolo Muratori, Piero L Almasio, Pietro Andreone, Marzia Margotti, Maurizia Brunetto, Barbara Coco, Domenico Alvaro, Maria C Bragazzi, Fabio Marra, Alessandro Pisano, Cristina Rigamonti, Massimo Colombo, Marco Marzioni, Antonio Benedetti, Luca Fabris, Mario Strazzabosco, Piero Portincasa, Vincenzo O Palmieri, Claudio Tiribelli, Lory Croce, Savino Bruno, Sonia Rossi, Maria Vinci, Cleofe Prisco, Alberto Mattalia, Pierluigi Toniutto, Antonio Picciotto, Andrea Galli, Carlo Ferrari, Silvia Colombo, Giovanni Casella, Lorenzo Morini, Nicola Caporaso, Agostino Colli, Giancarlo Spinzi, Renzo Montanari, Peter K Gregersen, E Jenny Heathcote, Gideon M Hirschfield, Katherine A Siminovitch, Christopher I Amos, M Eric Gershwin, Michael F Seldin
发表日期
2010/8
期刊
Nature genetics
卷号
42
期号
8
页码范围
658-660
出版商
Nature Publishing Group US
简介
A genome-wide association screen for primary biliary cirrhosis risk alleles was performed in an Italian cohort. The results from the Italian cohort replicated IL12A and IL12RB associations, and a combined meta-analysis using a Canadian dataset identified newly associated loci at SPIB (P = 7.9 × 10−11, odds ratio (OR) = 1.46), IRF5-TNPO3 (P = 2.8 × 10−10, OR = 1.63) and 17q12-21 (P = 1.7 × 10−10, OR = 1.38).
引用总数
学术搜索中的文章
X Liu, P Invernizzi, Y Lu, R Kosoy, Y Lu, I Bianchi… - Nature genetics, 2010