作者
Nilanjan Ghosh, Asif Ali, Rituparna Ghosh, Shaileyee Das, Subhash C Mandal, Mahadeb Pal
发表日期
2016/1/1
来源
Current Pharmaceutical Design
卷号
22
期号
2
页码范围
247-264
出版商
Bentham Science Publishers
简介
Diseases associated with chronic inflammatory pathology claim a major share of worldwide deaths each year. A principal reason behind the huge number of casualties is associated with mild or unnoticed symptoms for long period of time since the outset, and that specific treatment options for these diseases have not yet emerged. Current anti-inflammatory drugs essentially have become ineffective for long term protection from these diseases as they also interfere with essential cellular pathways and associated toxicities. Notably, recent studies with a number of phytochemicals have shown promising results. These compounds isolated from various medicinal plants express their anti-inflammatory activities by down regulating expression of several crucial pro-inflammatory mediators. These are mostly antioxidants; inhibit induction of key transcription factors like nuclear factor kappa B (NF-κB) that are responsible for …
引用总数
20162017201820192020202120222023264452
学术搜索中的文章
N Ghosh, A Ali, R Ghosh, S Das, SC Mandal, M Pal - Current Pharmaceutical Design, 2016