作者
Chin-Chun Chang, Chih-Jen Cheng, Chih-Chien Sung, Tzong-Shi Chiueh, Chien-Hsing Lee, Tom Chau, Shih-Hua Lin
发表日期
2013/11
期刊
European Journal of Endocrinology
卷号
169
期号
5
页码范围
529-536
出版商
Oxford University Press
简介
Background
A comprehensive analysis has not been performed on patients with thyrotoxic periodic paralysis (TPP) characterized by acute hypokalemia and paralysis in the setting of thyrotoxicosis.
Purpose
The aim of this study was to analyze the detailed symptomatology of thyrotoxicosis and precipitating factors for the attack in a large cohort of TPP patients.
Patients and methods
A prospective observational study enrolled patients with TPP consecutively over 10 years at an academic medical center. Clinical features, including signs/symptoms of thyrotoxicosis and precipitating factors, were analyzed. The Wayne's index was used to assess the severity of thyrotoxicosis at presentation. Patients who agreed to receive an oral glucose-loading test after recovery were evaluated.
Results
Among the 135 TPP patients (male:female, 130:5 …
学术搜索中的文章
CC Chang, CJ Cheng, CC Sung, TS Chiueh, CH Lee… - European Journal of Endocrinology, 2013