作者
Seiichiro Yamamoto, Masafumi Inomata, Hiroshi Katayama, Junki Mizusawa, Tsuyoshi Etoh, Fumio Konishi, Kenichi Sugihara, Masahiko Watanabe, Yoshihiro Moriya, Seigo Kitano, Japan Clinical Oncology Group Colorectal Cancer Study Group
发表日期
2014/7/1
来源
Annals of surgery
卷号
260
期号
1
页码范围
23-30
出版商
LWW
简介
Objective:
A randomized controlled trial to confirm the non-inferiority of laparoscopic surgery to open surgery in terms of overall survival was conducted, and short-term surgical outcomes are demonstrated.
Background:
The efficacy and safety outcome of laparoscopic surgery for clinical stages II/III colon cancer undergoing Japanese D3 dissection are still unclear.
Methods:
Eligibility criteria included colon cancer; tumor located in the cecum, ascending, sigmoid, or rectosigmoid colon; T3 or T4 without involvement of other organs; N0–2; and M0. Patients were randomized preoperatively and underwent tumor resection with D3 dissection. Safety analyses were conducted by per-protocol set.
Results:
A total of 1057 patients were randomized between October 2004 and March 2009. By per-protocol set, 524 patients who underwent open surgery and 533 patients who underwent laparoscopic surgery were analyzed. D3 …
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