作者
Anne M Dubin, Jan Janousek, Edward Rhee, Margaret J Strieper, Frank Cecchin, Ian H Law, Kevin M Shannon, Joel Temple, Eric Rosenthal, Frank J Zimmerman, Andrew Davis, Peter P Karpawich, Amin Al Ahmad, Victoria L Vetter, Naomi J Kertesz, Maully Shah, Christopher Snyder, Elizabeth Stephenson, Mathias Emmel, Shubhayan Sanatani, Ronald Kanter, Anjan Batra, Kathryn K Collins
发表日期
2005/12/20
期刊
Journal of the American College of Cardiology
卷号
46
期号
12
页码范围
2277-2283
出版商
American College of Cardiology Foundation
简介
Objectives
Our objective was to evaluate the short-term safety and efficacy of cardiac resynchronization therapy (CRT) in children.
Background
Cardiac resynchronization therapy has been beneficial for adult patients with poor left ventricular function and intraventricular conduction delay. The efficacy of this therapy in the young and in those with congenital heart disease (CHD) has not yet been established.
Methods
This is a multi-center, retrospective evaluation of CRT in 103 patients from 22 institutions.
Results
Median age at time of implantation was 12.8 years (3 months to 55.4 years). Median duration of follow-up was four months (22 days to 1 year). The diagnosis was CHD in 73 patients (71%), cardiomyopathy in 16 (16%), and congenital complete atrioventricular block in 14 (13%). The QRS duration before pacing was 166.1 ± 33.3 ms, which decreased after CRT by 37.7 ± 30.7 ms (p < 0.01). Pre-CRT systemic …
引用总数
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AM Dubin, J Janousek, E Rhee, MJ Strieper, F Cecchin… - Journal of the American College of Cardiology, 2005