作者
Susan P Etheridge, Carolina A Escudero, Andrew D Blaufox, Ian H Law, Brynn E Dechert-Crooks, Elizabeth A Stephenson, Anne M Dubin, Scott R Ceresnak, Kara S Motonaga, Jonathan R Skinner, Luciana D Marcondes, James C Perry, Kathryn K Collins, Stephen P Seslar, Michel Cabrera, Orhan Uzun, Bryan C Cannon, Peter F Aziz, Peter Kubuš, Ronn E Tanel, Santiago O Valdes, Sara Sami, Naomi J Kertesz, Jennifer Maldonado, Christopher Erickson, Jeremy P Moore, Hiroko Asakai, LuAnn Mill, Mark Abcede, Zebulon Z Spector, Shaji Menon, Mark Shwayder, David J Bradley, Mitchell I Cohen, Shubhayan Sanatani
发表日期
2018/4
期刊
JACC: Clinical Electrophysiology
卷号
4
期号
4
页码范围
433-444
出版商
American College of Cardiology Foundation
简介
Objectives
This study sought to characterize risk in children with Wolff-Parkinson-White (WPW) syndrome by comparing those who had experienced a life-threatening event (LTE) with a control population.
Background
Children with WPW syndrome are at risk of sudden death.
Methods
This retrospective multicenter pediatric study identified 912 subjects ≤21 years of age with WPW syndrome, using electrophysiology (EPS) studies. Case subjects had a history of LTE: sudden death, aborted sudden death, or atrial fibrillation (shortest pre-excited RR interval in atrial fibrillation [SPERRI] of ≤250 ms or with hemodynamic compromise); whereas subjects did not. We compared clinical and EPS data between cases and subjects.
Results
Case subjects (n = 96) were older and less likely than subjects (n = 816) to have symptoms or documented tachycardia. Mean age at LTE was 14.1 ± 3.9 years of age. The LTE was the …
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SP Etheridge, CA Escudero, AD Blaufox, IH Law… - JACC: Clinical Electrophysiology, 2018