作者
Raquel Araujo-Gutierrez, Kalyan R Chitturi, Jiaqiong Xu, Yuanchen Wang, Elizabeth Kinder, Alpana Senapati, L Bindu Chebrolu, Mahwash Kassi, Barry H Trachtenberg
发表日期
2021/12
期刊
Cardio-Oncology
卷号
7
页码范围
1-8
出版商
BioMed Central
简介
Background
Cancer therapy-related cardiac dysfunction (CTRD) is a major source of morbidity and mortality in long-term cancer survivors. Decreased GLS predicts decreased left ventricular ejection fraction (LVEF) in patients receiving anthracyclines, but knowledge regarding the clinical utility of baseline GLS in patients at low-risk of (CTRD) is limited.
Objectives
The purpose of this study was to investigate whether baseline echocardiographic assessment of global longitudinal strain (GLS) before treatment with anthracyclines is predictive of (CTRD) in a broad cohort of patients with normal baseline LVEF.
Methods
Study participants comprised 188 patients at a single institution who underwent baseline 2-dimensional (2D) speckle-tracking echocardiography before treatment with anthracyclines and at least one follow-up …
学术搜索中的文章
R Araujo-Gutierrez, KR Chitturi, J Xu, Y Wang, E Kinder… - Cardio-Oncology, 2021