作者
Ivan Urits, Jacquelin Peck, Mariam Salisu Orhurhu, John Wolf, Riki Patel, Vwaire Orhurhu, Alan D Kaye, Omar Viswanath
发表日期
2019/9
来源
Current pain and headache reports
卷号
23
页码范围
1-10
出版商
Springer US
简介
Purpose of Review
While clinicians have been using antidepressants for off-label indications in the treatment of chronic pain in recent years, newer studies have proven effectiveness and provided additional mechanistic understanding and defined potential adverse effects. As depression and chronic pain are frequently comorbid conditions, the use of antidepressants has allowed for treatment of both conditions concomitantly in the same patient population.
Recent Findings
The most commonly used antidepressants for chronic pain are tricyclic antidepressants (TCAs), though selective serotonin or noradrenaline reuptake inhibitors and other atypical antidepressants have been shown to be effective at treating chronic pain. In addition to neuropathic pain, bupropion has also demonstrated effectiveness in treating chronic pain caused by inflammatory bowel …
学术搜索中的文章
I Urits, J Peck, MS Orhurhu, J Wolf, R Patel, V Orhurhu… - Current pain and headache reports, 2019