作者
Mirza Muhammad Faran Ashraf Baig, Xiuli Gao, Muhammad Ajmal Khan, Awais Farid, Abdul Wasy Zia, Hongkai Wu
发表日期
2022/11/1
期刊
International Journal of Biological Macromolecules
卷号
220
页码范围
520-527
出版商
Elsevier
简介
Nanoscale double-crossovers (DX), antiparallel (A), and even half-turns-perimeter (E) DNA tiles (DAE-tiles) with rectangular shapes can be packed into large arrays of micrometer-scale lattices. But the features and mechanical strength of DNA assembly made from differently shaped large-sized DAE DNA tiles and the effects of various geometries on the final DNA assembly are yet to be explored. Herein, we focused on examining DNA lattices synthesized from DX bi-triangular, DNA tiles (T) with concave and convex regions along the perimeter of the tiles. The bi-triangular DNA tiles “T(A) and T(B)” were synthesized by self-assembling the freshly prepared short circular scaffold (S) strands “S(A) and S(B)”, each of 106 nucleotides (NT) lengths. The tiles “T(A) and T(B)” were then coupled together to get assembled via sticky ends. It resulted in the polymerization of DNA tiles into large-sized DNA lattices with giant …
引用总数
学术搜索中的文章
MMFA Baig, X Gao, MA Khan, A Farid, AW Zia, H Wu - International Journal of Biological Macromolecules, 2022