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This study aimed to investigate the interaction between dietary inflammatory index (DII) and apolipoproteinA2 265T > C (ApoA2 −265T > C) polymorphism on inflammatory and oxidative markers and lipid profile in type 2 diabetes mellitus (T2DM) patients.

In this cross‐sectional study, 157 patients with T2DM were recruited. A food‐frequency questionnaire was used for DII calculation. Inflammatory, oxidative and lipid biomarkers were measured. Real‐time polymerase chain reaction (PCR) method was used for ApoA2 genotyping determination.

In the current study, serum 8‐iso‐PGF2α and CRP were significantly higher, and serum SOD activity was significantly lower in subjects with CC genotype than TT homozygous in both crude and adjusted (for DII and AAs intake) models. Also, C‐allele carriers compared with people with TT genotype had lower PTX3 in both models. In addition …