作者
J Pieter Noordzij, Stephanie L Lee, Victor J Bernet, Richard J Payne, Seth M Cohen, Ian K McLeod, Michael P Hier, Martin J Black, Paul D Kerr, Melanie L Richards, Chung Yau Lo, Marco Raffaelli, Rocco Bellantone, Celestino P Lombardi, James I Cohen, Mary S Dietrich
发表日期
2007/12/1
期刊
Journal of the American College of Surgeons
卷号
205
期号
6
页码范围
748-754
出版商
No longer published by Elsevier
简介
BACKGROUND
Monitoring for hypocalcemia after thyroidectomy, using only symptoms and serum calcium levels, can delay the discharge of patients who will remain normocalcemic and can delay the treatment of hypocalcemic patients.
STUDY DESIGN
We conducted a systematic search for articles describing use of parathyroid hormone (PTH) assay, checked within hours of completing thyroidectomy, to predict postoperative symptomatic hypocalcemia. Studies were excluded if all patients were treated with postoperative calcium, or if early PTH values were used to alter management of the patient. Individual patient data (perioperative PTH and calcium levels, development of hypocalcemia) were obtained for 457 patients from the corresponding authors of 9 studies and pooled to yield the following results.
RESULTS
PTH, checked at three time periods after removal of the thyroid gland (0 to 20 minutes, 1 to 2 hours …
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