作者
Anh Tu Duy Nguyen, Vincent Jobin, Richard Payne, Josée Beauregard, Naftaly Naor, R John Kimoff
发表日期
2005/5/1
期刊
Sleep
卷号
28
期号
5
页码范围
585-593
出版商
Oxford University Press
简介
Study Objective
To determine whether mucosal sensory dysfunction is present at multiple upper-airway sites in patients with obstructive sleep apnea (OSA).
Design
Physiologic testing of consecutive patients with OSA and nonsnoring controls.
Setting
University hospital sleep center.
Participants
Thirty-nine subjects with OSA and 17 controls.
Interventions
Endoscopic testing was used to determine sensory detection thresholds for air-pressure pulses delivered to the oropharynx, velopharynx, hypopharynx, and larynx (aryepiglottic eminence). The air-pulse stimulus intensity required to elicit the protective laryngeal adductor reflex was also determined.
Measurements and Results
There was a significant impairment in sensory detection threshold for OSA versus control subjects in the oropharynx …
引用总数
学术搜索中的文章
ATD Nguyen, V Jobin, R Payne, J Beauregard, N Naor… - Sleep, 2005