作者
C Klinger, M Snape, A Pollard, S Baker, D Scott, SN Faust, T John, H Layton, E Daniels, S Tansey, W Gruber, S Pestridge, A Finn, S Dymond, PT Heath, E Galiza
发表日期
2008
简介
Background
Streptococcus pneumoniae is a leading cause of morbidity and mortality in children worldwide. Although the 7-valent pneumococcal conjugate vaccine (PCV7) has been successful in controlling pneumococcal disease, some disease-causing serotypes are not covered by this vaccine. We report the infant series results of a randomised, double-blind, active-controlled study of a 13-valent-pneumococcal vaccine (PCV13), containing polysaccharides from serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 23F individually conjugated to CRM197.
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C Klinger, M Snape, A Pollard, S Baker, D Scott… - 2008