作者
Mahfuz Elmastas, Ramazan Erenler, Besir Isnac, Huseyin Aksit, Ozkan Sen, Nusret Genc, Ibrahim Demirtas
发表日期
2016/2/1
期刊
Natural Product Research
卷号
30
期号
3
页码范围
299-304
出版商
Taylor & Francis
简介
Teucrium chamaedrys L. is an aromatic and medicinal plant used as traditional medicine. Aerial parts of the plant material were dried and extracted with hexane–dichloromethane (extract 1), ethyl acetate–dichloromethane (extract 2) and methanol–dichloromethane (extract 3) in a ratio of 1:1 at rt successively. The solvents were evaporated to give crude extracts. Extract 1 was suspended in water at 60°C then partitioned successively with hexane and ethyl acetate to give hexane and ethyl acetate portions. After the column chromatography (silica gel) of ethyl acetate extract, one new and four known compounds were isolated. The new compound was named as 1(12S,18R)-15,16-epoxy-2β,6β-dihydroxy-neo-cleroda-13(16),14-dien-20,l2-olide-l8,l9-hemiacetal (teuchamaedryn D) (4). The known compounds were teucrin A (1), dihydroteugin (2), teucroxide (3), syspirensin A (5). The chromatographic methods were also …
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M Elmastas, R Erenler, B Isnac, H Aksit, O Sen, N Genc… - Natural Product Research, 2016