作者
Gordon H Guyatt, Andrew D Oxman, Mahmoud Ali, Andrew Willan, William McIlroy, Christopher Patterson
发表日期
1992/3
来源
Journal of general internal medicine
卷号
7
页码范围
145-153
出版商
Springer-Verlag
简介
Background and methods:To determine the diagnostic values of laboratory tests used in the diagnosis of iron-deficiency anemia, the authors conducted a systematic over-view of the relevant literature. Computerized searches of the MEDLINE database yielded 1,179 potentially relevant citations. Fifty-five studies included the results of laboratory tests and histologic examination of the bone marrow for at least 50% of an identifiable patient group. In these 55 studies, quality was assessed and descriptive information concerning the study populations, the tests conducted, and the results was extracted, all in duplicate.
Results:Serum ferritin radioimmunoassay was by far the most powerful test, with an area under the receiver operating characteristic curve of 0.95. Test properties differed for populations of patients with inflammatory, liver, or neoplastic disease and patients without these conditions …
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GH Guyatt, AD Oxman, M Ali, A Willan, W McIlroy… - Journal of general internal medicine, 1992