作者
Jonathan I Silverberg, Joel M Gelfand, David J Margolis, Mark Boguniewicz, Luz Fonacier, Mitchell H Grayson, Peck Y Ong, Zelma Chiesa Fuxench, Eric L Simpson
发表日期
2019/4/1
期刊
The Journal of Allergy and Clinical Immunology: In Practice
卷号
7
期号
4
页码范围
1246-1252. e1
出版商
Elsevier
简介
Background
The impact of atopic dermatitis (AD) on health-related quality of life and health utility in the US adult population is not well established.
Objective
To determine the health utilities and quality-adjusted life-years (QALYs) lost in adults with AD versus without AD in the US population.
Methods
A cross-sectional, population-based study of 3495 adults was performed. AD was determined using modified UK diagnostic criteria for AD. AD severity was assessed using self-reported global AD severity, the Patient-Oriented Eczema Measure, the Patient-Oriented Scoring AD, and the Patient-Oriented Scoring AD itch and sleep. Six-dimensional health state short form (SF-6D) health utility scores and total QALY loss were assessed.
Results
The mean SF-6D score was lower in adults with AD compared with healthy adults (0.69 [95% CI, 0.68-0.70] versus 0.79 [95% CI, 0.77-0.79]). In particular, those with moderate-to-severe …
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JI Silverberg, JM Gelfand, DJ Margolis, M Boguniewicz… - The Journal of Allergy and Clinical Immunology: In …, 2019