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The BioFire® FilmArray® Blood Culture Identification 2 (BCID2) panel is a rapid diagnostic tool that uses multiplex polymerase chain reaction technology to identify 43 different genetic targets. BCID2 detects 13 additional targets, including 7 resistance markers, not detected by the original BCID panel. For this reason, our institution changed panels from BCID to BCID2 in August 2020. The purpose of this study was to assess the time to antibiotic change for Enterobacterales bloodstream infections before and after switch to BCID2.

This was a retrospective, observational, before-and-after study conducted at an 885-bed academic medical center. Adult patients with blood cultures positive for E. coli or K. pneumoniae (EC/KP) who received broad spectrum beta-lactam therapy were included. Patients with a polymicrobial or concurrent infection, hemodynamic …