作者
Sandro M Krieg, Jamil Sabih, Lucia Bulubasova, Thomas Obermueller, Chiara Negwer, Insa Janssen, Ehab Shiban, Bernhard Meyer, Florian Ringel
发表日期
2014/9/1
期刊
Neuro-oncology
卷号
16
期号
9
页码范围
1274-1282
出版商
Oxford University Press
简介
Background
Navigated transcranial magnetic stimulation (nTMS) has been proven to influence surgical indication and planning. Yet there is still no clear evidence how these additional preoperative functional data influence the clinical course and outcome. Thus, this study aimed to compare patients with motor eloquently located supratentorial lesions investigated with or without preoperative nTMS in terms of clinical outcome parameters.
Methods
A prospectively enrolled cohort of 100 patients with supratentorial lesions located in motor eloquent areas was investigated by preoperative nTMS (2010–2013) and matched with a control of 100 patients who were operated on without nTMS data (2006–2010) by a matched pair analysis.
Results
Patients in the nTMS group showed a significantly lower rate of residual tumor on postoperative MRI (OR 0.3828; 95 …
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SM Krieg, J Sabih, L Bulubasova, T Obermueller… - Neuro-oncology, 2014