作者
René Rizzoli, Jean-Yves Reginster, Jean-François Arnal, Ivan Bautmans, Charlotte Beaudart, Heike Bischoff-Ferrari, Emmanuel Biver, Steven Boonen, Maria-Luisa Brandi, Arkadi Chines, Cyrus Cooper, Sol Epstein, Roger A Fielding, Bret Goodpaster, John A Kanis, Jean-Marc Kaufman, Andrea Laslop, Vincenzo Malafarina, Leocadio Rodriguez Mañas, Bruce H Mitlak, Richard O Oreffo, Jean Petermans, Kieran Reid, Yves Rolland, Avan Aihie Sayer, Yannis Tsouderos, Marjolein Visser, Olivier Bruyère
发表日期
2013/8
来源
Calcified tissue international
卷号
93
页码范围
101-120
出版商
Springer US
简介
The reduced muscle mass and impaired muscle performance that define sarcopenia in older individuals are associated with increased risk of physical limitation and a variety of chronic diseases. They may also contribute to clinical frailty. A gradual erosion of quality of life (QoL) has been evidenced in these individuals, although much of this research has been done using generic QoL instruments, particularly the SF-36, which may not be ideal in older populations with significant comorbidities. This review and report of an expert meeting presents the current definitions of these geriatric syndromes (sarcopenia and frailty). It then briefly summarizes QoL concepts and specificities in older populations and examines the relevant domains of QoL and what is known concerning QoL decline with these conditions. It calls for a clearer definition of the construct of disability, argues that a disease-specific QoL instrument …
学术搜索中的文章
R Rizzoli, JY Reginster, JF Arnal, I Bautmans… - Calcified tissue international, 2013