作者
Martha Gulati, Rhonda M Cooper-DeHoff, Candace McClure, B Delia Johnson, Leslee J Shaw, Eileen M Handberg, Issam Zineh, Sheryl F Kelsey, Morton F Arnsdorf, Henry R Black, Carl J Pepine, C Noel Bairey Merz
发表日期
2009/5/11
期刊
Archives of internal medicine
卷号
169
期号
9
页码范围
843-850
出版商
American Medical Association
简介
Background
Women with clinical findings suggestive of ischemia but without findings of obstructive coronary artery disease (CAD) on angiography represent a frequent clinical problem; predicting prognosis is challenging.
Methods
The Women's Ischemia Syndrome Evaluation (WISE) study examined symptomatic women referred for clinically indicated coronary angiography and followed up for a mean 5.2 years. The St James Women Take Heart (WTH) Project enrolled asymptomatic, community-based women with no history of heart disease who were followed up for 10 years. We compared cardiovascular events (ie, myocardial infarction, stroke, and hospitalization for heart failure) and death in 540 WISE women with suspected ischemia but no angiographic evidence of obstructive CAD with those from a cohort of 1000 age- and race-matched WTH women.
Results
Compared with the WISE women, asymptomatic WTH …
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