作者
Teivi Laurimäe, Liina Kinkar, Thomas Romig, Gérald Umhang, Adriano Casulli, Rihab A Omer, Mitra Sharbatkhori, Hossein Mirhendi, Francisco Ponce-Gordo, Lorena E Lazzarini, Silvia V Soriano, Antonio Varcasia, Mohammad Rostami-Nejad, Vanesa Andresiuk, Pablo Maravilla, Luis Miguel González, Monika Dybicz, Jakub Gawor, Mindaugas Šarkūnas, Viliam Šnábel, Tetiana Kuzmina, Eshrat Beigom Kia, Urmas Saarma
发表日期
2019/10/1
期刊
Infection, Genetics and Evolution
卷号
74
页码范围
103941
出版商
Elsevier
简介
The larval stages of tapeworms in the species complex Echinococcus granulosus sensu lato cause a zoonotic disease known as cystic echinococcosis (CE). Within this species complex, genotypes G6 and G7 are among the most common genotypes associated with human CE cases worldwide. However, our understanding of ecology, biology and epidemiology of G6 and G7 is still limited. An essential first step towards this goal is correct genotype identification, but distinguishing genotypes G6 and G7 has been challenging. A recent analysis based on complete mitogenome data revealed that the conventional sequencing of the cox1 (366 bp) gene fragment mistakenly classified a subset of G7 samples as G6. On the other hand, sequencing complete mitogenomes is not practical if only genotype or haplogroup identification is needed. Therefore, a simpler and less costly method is required to distinguish genotypes …
引用总数
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