作者
Liina Kinkar, Teivi Laurimäe, Mitra Sharbatkhori, Hossein Mirhendi, Eshrat Beigom Kia, Francisco Ponce-Gordo, Vanessa Andresiuk, Sami Simsek, Antti Lavikainen, Malik Irshadullah, Gérald Umhang, Myriam Oudni-M'Rad, Gerardo Acosta-Jamett, Steffen Rehbein, Urmas Saarma
发表日期
2017/8/1
期刊
Infection, Genetics and Evolution
卷号
52
页码范围
52-58
出版商
Elsevier
简介
Cystic echinococcosis, a zoonotic disease caused by Echinococcus granulosus sensu lato (s. l.), is a significant global public health concern. Echinococcus granulosus s. l. is currently divided into numerous genotypes (G1–G8 and G10) of which G1–G3 are the most frequently implicated genotypes in human infections. Although it has been suggested that G1–G3 could be regarded as a distinct species E. granulosus sensu stricto (s. s.), the evidence to support this is inconclusive. Most importantly, data from nuclear DNA that provide means to investigate the exchange of genetic material between G1–G3 is lacking as none of the published nuclear DNA studies have explicitly included G2 or G3. Moreover, the commonly used relatively short mtDNA sequences, including the complete cox1 gene, have not allowed unequivocal differentiation of genotypes G1–G3. Therefore, significantly longer mtDNA sequences are …
引用总数
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