作者
Kenji Hirano, Yasushi Shiratori, Yutaka Komatsu, Natsuyo Yamamoto, Naoki Sasahira, Nobuo Toda, Hiroyuki Isayama, Minoru Tada, Takeshi Tsujino, Ryo Nakata, Tateo Kawase, Tetsuo Katamoto, Takao Kawabe, Masao Omata
发表日期
2003/11/1
期刊
Clinical Gastroenterology and Hepatology
卷号
1
期号
6
页码范围
453-464
出版商
WB Saunders
简介
Background & Aims
The aim of this study was to define the bile duct changes associated with autoimmune pancreatitis.
Methods
Eight patients with autoimmune pancreatitis were followed for a mean of 4 years. The clinical features of these patients, including extrapancreatic bile duct changes, were examined by using biochemical parameters and several imaging modalities. Pathologic features of the pancreas and liver were examined by using the biopsy specimens of 7 patients.
Results
Diffuse or focal narrowing of the main pancreatic duct was observed in all patients. Histologic examination of the pancreas showed lymphoplasmacyte infiltration with severe fibrosis and acinar cell depletion. In 6 patients extrapancreatic bile duct changes such as stricture of the bile duct at hilus or intrahepatic area were observed. In 2 patients abnormalities in the bile duct and pancreas were detected simultaneously at diagnosis …
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K Hirano, Y Shiratori, Y Komatsu, N Yamamoto… - Clinical Gastroenterology and Hepatology, 2003